Vue Cinema Portsmouth is dedicated to providing accessibility for all guests. The venue has wheelchair access throughout, with step-free access to wheelchair spaces and adjoining seats in all screens. There are also accessible toilets off the main foyer. Additionally, the venue offers HOH headsets for customers with hearing impairments.

Vue Cinema Portsmouth is conveniently located on the first floor of the Gunwharf Quays shopping centre, with both lift and escalator access. There is plenty of blue badge parking available in the shopping centre's car park, as well as a drop off point for cars and taxis nearby. The train station is next door to the venue, and bus stops are just a five-minute walk away.

Customers can purchase tickets for screenings at Vue Cinema Portsmouth either online, in person at the venue, or by calling customer services. For those using the CEA card, tickets can be purchased in person at the venue, online, or by calling customer services. Film times are updated each Wednesday morning for the coming Friday.

Vue Cinema Portsmouth shows subtitled (ST) films every week, with film times updated each Wednesday morning for the coming Friday. Customers can book subtitled screenings online. Additionally, the venue offers accessible and autism-friendly screenings for a more inclusive movie-watching experience.